Conference “A New Path to Pharmacology Using Cell-Penetrating Peptides”

On March 6, 2026 at 11:00, a scientific conference “A New Path to Pharmacology Using Cell-Penetrating Peptides” will take place at the Estonian Academy of Sciences (Kohtu 6, Tallinn).

The conference will present the latest research results on shuttle peptides (cell-penetrating peptides, CPP). These peptides enable the molecules attached to them to cross biological barriers and allow the efficient transport of small drug molecules as well as RNA and DNA molecules and nanoparticles. This opens up new possibilities for developing medicines capable of effectively crossing biological barriers and advances a new type of pharmacology.

The conference is organized by Tallinn University of Technology, the Estonian Academy of Sciences, the Estonian Biochemical Society, and the Estonian Chemical Society.

To participate, please register via online form no later than February 26. Participation is free of charge.

PROGRAMME

Moderated bt Ly Villo and Pirjo Spuul

11.00Opening
Anne Kahru, Secretary General of the Estonian Academy of Sciences
11.10Introduction
Tiit Land, Professor, Rector of Taltech, Tallinn
(Title TBA)
11.30Remarks on the way to new pharmacology
Ülo Langel, Professor Emeritus, Stockholm University and Tartu University
12.00Crossing Cellular Barriers: CPP Applications from Lab to Therapy
Prisca Boisguérin, Professor, University of Montpellier, INSERM, CNRS, and Bâtiment Institut Universitaire de Recherche Clinique, Montpellier, France
12.30From a chimeric peptide M384 to nanoparticles for RNA delivery in vivo
Margus Pooga, PhD, Tartu University, Estonia
13.00Coffee break
13.45An overview of the molecular mechanisms involved in cell-penetrating peptide translocation
Sandrine Sagan, Professor, Sorbonne Université, École Normale Supérieure, PSL University, CNRS, Chimie Physique et Chimie du Vivant, Paris, France (TBA)
14.15Tissue- and disease-specific homing and penetrating peptides: discovery and applications for precision medicine
Tambet Teesalu, Professor, Tartu University, Estonia
14.45From Barriers to Boulevards: Cell-Penetrating Peptides as Programmable Intracellular Taxis
James Eberwine, Professor, Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA
15.15Originality of design and not missing an unexpected outcome; Chimeric Peptide antagonists and Cell Penetrating Peptides starting with Galanin Receptor ligands
Tamas Bartfai, Professor Emeritus, Stockholm University, and University of Pennsylvania, USA
15.45Carbon-to-nitrogen atom swap in peptides for pharmacological application
Jaak Järv, Professor Emeritus, University of Tartu, Estonia
15.30Concluding remarks and general discussion
Jaak Järv, Professor Emeritus, University of Tartu, Member of the Estonian Academy of Sciences, Estonia
16.00Concluding remarks and general discussion
Jaak Järv, Professor Emeritus, University of Tartu, Member of the Estonian Academy of Sciences, Estonia
16.45End of the Conference